Support for Your Concerns by Product and Industry!

by Malvern Panalytical, Wednesday, 5th February 2025

Hello!
This page is designed to help resolve common issues for users of particle size analyzers.
Additionally, it provides insights into why customers decided to implement these devices (customer stories),
and summarizes how our company can contribute to better products and increase efficiency.

Table of Contents

〇 Common Troubles During Measurement 〇

Laser Diffraction/Scattering Method Particle Size Distribution Measurement Devices

  1. Can’t identify the right product for your company
  2. Considering a replacement? Challenges with equipment differences and data migration, and their solutions
  3. Common causes and solutions for weird data in particle size distribution measurements
  4. Inclusion of foreign large particles prevents accurate measurement
  5. Want to measure paste or micro samples
  6. Difficulty in method (test procedure) settings and optimization
  7. Differences in experience levels affect measurement results
  8. Want to ensure measurement results
  9. Want to measure in real-time at the factory, etc.
Particle Size Distribution Jp
Particle size analyzer selector

Zeta Potential Measurement Devices

  1. Can’t identify the right product for your company
  2. Unable to accurately measure zeta potential when salt concentration is high
  3. Particles to be measured are near the performance limit in terms of size
  4. Unsure if the obtained results are reliable
  5. Limited resolution
  6. Sample changes rapidly, messing up measurements
  7. Uncertain about the particle concentration
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〇 Be Inspired by Other Companies’ Stories! Customer Stories 〇

The following articles are in English. You can translate them to Japanese by right-clicking.

Laser Diffraction Particle Size Distribution Analyzer: Mastersizer Edition

Case Study 1: Metals and Additives LLC (Leading manufacturer of powder additives for the battery and plastics industry)

◎ Problems & Desired Outcomes
Metals and Additives LLC considers particle size analysis a crucial part of their testing processes. Since they deal with dry powders, wet analysis posed numerous challenges, necessitating a more versatile device.

◎ Comparison & Consideration
When considering a purchase, they compared five devices based on criteria including precision, accuracy, user-friendliness, and cost. Ultimately, Malvern Panalytical’s Mastersizer 3000 stood out, meeting most of the criteria.

◎ Result of Implementation
The Mastersizer 3000 significantly improved throughput, resulting in highly reproducible results. It enabled both wet and dry analyses, with minimal maintenance and superb user-friendliness.

For more details, please click here.

Case Study 2: Jan De Nul Group (Specialized provider of services for oil, gas, renewable energy offshore markets)

◎ Problems & Desired Outcomes
The company undertakes projects involving the design, development, and maintenance of ports, dredging of canals, land reclamation, and coastal protection works. They needed a new system that met several requirements for swift and reliable particle analysis.

◎ Comparison & Consideration
Using a comprehensive approach to select a new particle size analysis system, Jan De Nul Group determined the Malvern Panalytical Mastersizer 3000 was the best solution. Its compact design makes it portable and easy to use with efficient analyses both in the field and lab.

◎ Implementation Outcome
The Mastersizer 3000 requires only a few grams per sample, allowing fast analysis that helps meet stringent tender deadlines. Its broad particle distribution range saves significant time compared to conventional methods. Additionally, an apparatus to evaluate the wear on pipelines predictive of costs was acquired through extensive evaluation of particle form analyzers. After thorough assessment, Jan De Nul Group chose Malvern Panalytical’s Morphologi G3SE. The device allows accurate particle size and shape analysis.

For more details, please click here.

Zeta Potential Measurement Device: Zetasizer Edition

Case Study 1: Dolomite Microfluidics (Developing and manufacturing pioneering technologies in biology, chemistry, microfluidics, and nanomaterials)

◎ Problems & Desired Outcomes
The Dolomite Microfluidics team meticulously controls particle size to optimize size-dependent functionalities like plasmon resonance and fluorescence efficiency. They were using Transmission Electron Microscopy (TEM), which is expensive and time-consuming, leading to inefficiency.

◎ Implementation Outcome
Using Malvern Panalytical’s Zetasizer Ultra enabled the team to swiftly characterize research samples, reducing data acquisition to under five minutes. Products can be analyzed shortly after synthesis, rapidly confirming quality control specifications. The reliable data provided by the Zetasizer Ultra offers a representative particle size distribution of the entire sample, significantly reducing TEM usage and streamlining R&D processes and quality control, leading to reduced analytical costs.

For more details, please click here.

Case Study 2: Polymun Scientific (Developing and manufacturing liposomal and LNP formulations)

◎ Problems & Desired Outcomes
Until 2020, liposomal and LNP formulations were niche applications. However, LNP-mRNA vaccines emerged as the most promising approach to combating the novel coronavirus, SARS-CoV-2. Polymun needed to scale up LNP production for the BioNtech-Pfizer COVID-19 vaccine.

◎ Implementation Outcome
Polymun established new analytical methods to control the manufacturing process and ensure batch-to-batch consistency and long-term stability of liposomal and LNP products. Malvern Panalytical’s Zetasizer DLS proves to be an essential tool for measuring the size and size distribution of liposomes and LNPs.

For more details, please click here.

〇 Industry-Specific Support 〇

Click the respective industry link to navigate to the relevant section.
(Many articles are in English. You can use the right-click translation feature to display them in Japanese.)

Pharmaceuticals
Food Analysis
Batteries
Metal Analysis
Chemical and Fine Chemicals
Building Materials
Nanomaterials

Pharmaceuticals

Food Analysis

Batteries

Metal Component Analysis

Chemical and Fine Chemicals

Building Materials

Nanomaterials

〇 Others 〇

〇 Free Seminar Information 〇

Malvern Panalytical offers free web seminars and individual consultation sessions periodically.
In-person consultations are available at our Tokyo and Kobe labs, where you can check samples and products.

A variety of past seminars have been held. Below are examples of seminars held in Japan.
Clicking on them may allow you to view some seminars for free. *Web registration is required.

While registering for the web, subscribe to receive email newsletters and seminar invitations.
If you are interested in individual consultations, please contact us here.

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Please tick the option for receiving email newsletters containing seminar information and more.
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