Pushing the boundaries in pharmaceutical hit discovery with the novel waveRAPID kinetic assay

In this technical note, conducted by an HTS drug discovery group of our customer Idorsia Pharmaceuticals Ltd, we demonstrate the power of Creoptix WAVE Rapid in streamlining the kinetic characterization of large numbers of drug hit compounds, with results comparable to traditional SPR and high reproducibility. With pulsed injections of each sample at a single concentration, contact times are reduced, preserving target protein, enabling longer runs and measuring hundreds of interactions in days rather than weeks.

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