Dynamic light scattering (DLS), sometimes referred to as Quasi Elastic Light Scattering (QELS), is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles typically in the submicron region, and with the latest technology, lower than 1nm.
Applications of DLS
Dynamic Light Scattering is a powerful analytical technique, and when coupled with advanced instruments like the Zetasizer Advance, it becomes indispensable across various industries.
Here's how the Zetasizer Advance, with its dynamic light scattering technique, offers unparalleled insights into particle size, stability, and interactions across a wide range of sectors:
Pharmaceuticals and Biotechnology
The Zetasizer Advance is instrumental in nanoparticle characterization for drug delivery systems, ensuring precise size distribution analysis crucial for drug efficacy and stability.
It facilitates the study of protein aggregation kinetics, enabling researchers to optimize protein formulations and ensure product quality in biopharmaceutical manufacturing.
Pharmaceutical solutions
Cosmetics and Personal Care
In the cosmetics industry, the Zetasizer Advance helps in characterizing the size and stability of colloidal dispersions, essential for the formulation of creams, lotions, and emulsions.
It aids in assessing the stability of nanoparticles in sunscreen formulations, ensuring effective UV protection and long-term stability of the product.
Food and Beverages
The Zetasizer Advance assists in analyzing the particle size distribution and aggregation behavior of food emulsions, influencing product texture, stability, and sensory attributes.
It is used to evaluate the stability of colloidal suspensions in beverages, ensuring product clarity and shelf-life stability.
Materials Science and Nanotechnology
In materials science, the Zetasizer Advance is employed for nanoparticle sizing and characterization, guiding the synthesis and optimization of functional nanomaterials for diverse applications.
It aids in studying the stability and aggregation kinetics of nanoparticles in coatings and composites, influencing material properties such as mechanical strength and optical transparency.
Environmental Monitoring
The Zetasizer Advance contributes to environmental monitoring efforts by analyzing the size distribution and aggregation behavior of nanoparticles in environmental samples, helping assess their impact on ecosystems and human health.
It aids in studying the behavior of engineered nanoparticles in wastewater treatment processes, ensuring efficient removal and minimizing environmental exposure.
Our DLS instruments
At Malvern Panalytical, we offer state-of-the-art DLS instruments designed to meet the diverse needs of researchers and industry professionals. Our Zetasizer Advance Range combines precision, reliability, and user-friendly features to deliver accurate and insightful data.
Key capabilities and advantages include:
- Accurate, reliable and repeatable particle size analysis in a few minutes
- Multi-Angle Dynamic Light Scattering (MADLS) improves the resolution of DLS and provides angular independent size results
- Simple measurement of per peak particle concentration
- Mean size only requires knowledge of the viscosity of the liquid
- Simple or no sample preparation, high concentration, turbid samples can be measured directly using NIBS
- Size measurement of sizes from <1 nm to 15 um
- Size measurement of molecules from MW < 1000 Da
- Low volume requirement (as little as 3 µL)
- At-line process systems available for control of nanoparticle manufacture
- Compliance with regulatory standards ISO 13321, ISO 22412, 21 CFR Part 11
