Viscosizer TD - protein stability characterization platform | Malvern Panalytical

Date recorded: July 11 2017

Duration: 32 minutes 37 seconds

Viscosizer TD is a key component of Malvern’s biopharmaceutical toolset, offering novel capabilities for biophysical characterization in complex solutions, particularly applicable in the early stages of the biopharmaceutical development workflow.

Viscosizer TD provides an orthogonal technique for characterization of molecular size, solution stability and self- association, as well as relative viscosity. Industrial researchers compiling predictive molecular stability profiles for early developability assessment must extrapolate the long-term stability behavior of therapeutic molecules from initial data in order to reduce development risk and cost. The fully-automated Viscosizer TD requires low sample volumes and provides a multivariate dataset output, enabling a more efficient and informed decision-making process.

Table of contents

1. Welcome

00:11

2. Introduction

01:50

3. Viscosizer TD:Protein Stability Characterization Platform

00:05

4. Untitled

00:11

5. Untitled

00:11

6. Untitled

00:12

7. Emerging Market - Towards novel biologics

00:34

8. Emerging Market - Towards novel biologics

00:44

9. Untitled

00:12

10. Untitled

00:19

11. Untitled

00:18

12. Protein stability profiling

00:12

13. Protein stability profiling

00:26

14. Viscosizer TD – Physical stability profiling

00:22

15. Viscosizer TD – Physical stability profiling

00:18

16. Viscosizer TD – Physical stability profiling

00:10

17. Untitled

00:33

18. Viscosizer TD – Instrument

00:16

19. Viscosizer TD – Instrument

00:33

20. Viscosizer TD – Instrument

00:27

21. Viscosizer TD – Instrument

00:28

22. Viscosizer TD – Instrument

00:13

23. Taylor Dispersion Analysis – Size

00:20

24. Taylor Dispersion Analysis – Size

00:50

25. Taylor Dispersion Analysis – Size

00:27

26. Untitled

00:35

27. Untitled

01:00

28. Untitled

00:47

29. Untitled

00:16

30. Taylor Dispersion Analysis – kD

01:28

31. Untitled

01:12

32. Untitled

00:52

33. Poiseuille Flow – Viscosity

00:15

34. Poiseuille Flow – Viscosity

00:14

35. Poiseuille Flow – Viscosity

00:03

36. Poiseuille Flow – Viscosity

00:02

37. Poiseuille Flow – Viscosity

00:04

38. Poiseuille Flow – Viscosity

00:14

39. Poiseuille Flow – Viscosity

00:05

40. Untitled

00:13

41. Measurement Capabilities

00:14

42. Measurement Capabilities

00:05

43. Measurement Capabilities

00:19

44. Untitled

00:20

45. Applications: Early developability screen of mAb candidates using TDA

00:41

46. Applications: Early developability screen of mAb candidates using TDA

00:20

47. Applications: Early developability screen of mAb candidates using TDA

00:18

48. Applications: Early developability screen of mAb candidates using TDA

00:34

49. Applications: Early developability screen of mAb candidates using TDA

00:05

50. Applications: Early developability screen of mAb candidates using TDA

00:05

51. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates

00:15

52. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates

00:38

53. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates

00:47

54. Applications: DLS vs. TDA for characterisation of peptide and protein aggregates

00:05

55. Applications: Peptide- peptide interaction analysis using TDA

00:55

56. Applications: Peptide- peptide interaction analysis using TDA

00:08

57. Applications: Aggregation of cyclodextrin-drug conjugate using TDA analysis

00:33

58. Summary

00:38

59. Any questions?

00:09

60. Thank you for your attentionAny questions?

07:30

61. Thank You!

00:16

Contact sales Register now