Date recorded: May 17 2018

Duration: 38 minutes 40 seconds

Multi-detector GPC/SEC offers superior information about polymers, including absolute molecular weight, size, and structure, when compared with conventional single-detector measurements. At the same time, UPLC offers a step-change in the resolution and speed of polymer separations, using small columns and particle sizes to achieve high plate counts. Previously these two techniques have been incompatible due to band-broadening and dispersion effects that take place as narrow UPLC peaks pass through multiple detector cells.The latest enhancements to Malvern Panalytical's OMNISEC REVEAL detector platform now bring these two class leading technologies together. Combining the information-rich data from multi-detector GPC/SEC with the speed and resolution afforded by UPLC (Water's ACQUITY APC).

This webinar will briefly describe advanced detection and UPLC, and discuss how these two technologies have been brought together. Application examples will be provided showing how this data really can be generated in just a few minutes.

Table of contents
1. Welcome
00:19
2. Mark Pothecary
00:06
3. Multi-detector UPLC
01:13
4. Size-exclusion chromatography
01:45
5. Overview of Multi-detector sec
00:11
6. Multi-detector SEC
01:34
7. Refractive index
00:57
8. UV-Vis Detection
01:01
9. Static light scattering
01:20
10. Intrinsic viscosity
01:20
11. Mark-Houwink plots
01:30
12. Branching
00:40
13. The multi-detection pyramid
01:12
14. Multi-detector SEC summary
00:21
15. Watersacquity APC
03:06
16. Waters ACQUITY APC
02:59
17. Multi-detector UPLCOMNISEC & APC
00:09
18. Why are we interested in UPLC?
01:27
19. Challenges involved with Multi-detection UPLC
01:08
20. Analytical GPC
00:38
21. Dispersion in UPLC
00:40
22. Hardware improvements
02:22
23. Dispersion in UPLC
01:00
24. Improve sensitivity
00:10
25. Sensitivity in analytical SEC
00:18
26. Sensitivity in UPLC
00:55
27. Improve measurement speed
00:08
28. Polystyrene Branching
01:28
29. PLA/PLGA
00:10
30. Copolymer PLGA 75:25
00:31
31. PLA/PLGA
00:38
32. Drug delivery polymer
01:41
33. Improve resolution
00:21
34. Oligomeric resolution
01:01
35. POlycaprolactone
00:05
36. PAO
02:17
37. Multi-detector UPLC
01:12
38. Thanks for listening
00:24
39. Contact Information
00:23