Zetasizer Nano Series

by Seungji Kim, Friday, 23rd September 2011

The new Zetasizer Nano series allows the measurement of the three most important parameters for the analysis of colloids and polymer compounds: particle size, zeta potential, and molecular weight. These instruments incorporate new technology that offers exceptional sensitivity and a wide range of functionalities. Malvern’s patented NIBS light technology is applied to the Nano Z and Nano ZS, allowing samples to be measured without dilution or with slight dilution. The Zetasizer Nano ZS is the top instrument in Malvern’s Zetasizer Nano series, capable of measuring all three parameters without performance adjustment.

The Nano ZS, Z, and ZS90 instruments all use Malvern Instrument’s proprietary disposable zeta potential cell, preventing contamination between samples.

* Particle Size – NIBS technique can measure the size of particles and molecules in the range of 0.3nm to 10µm.

* Zeta Potential – M3-PALS technology can accurately measure the zeta potential of samples in both aqueous and non-aqueous dispersants.

* Molecular Weight – Using an Avalanche Photodiode detector and fiber optic transmission devices provides the sensitivity and stability required for absolute molecular weight measurement.

▶ Product Specifications

1. Common Specifications

* Temperature range: 0°C – 90°C

     * Condensation air: Purge equipment using dry air/nitrogen
     * Laser: 4mW He-Ne, 633nm
     * Laser attenuator: Automatic, transmitted from 100% to 0.0003%
     * Detector: Avalanche Photodiode, Q.E: over 50% at 633nm
     * Laser class: Class 1 conforming to EN 60825-1:2001 and CDRH
     * Size: 320mm, 600mm, 260mm(W,D,H)
     * Weight: 21kg

2. By Parameter

** Size Measurement

	Nano ZS	Nano S	Nano Z	Nano ZS90	Nano S90
Particle Size Range (Diameter)	0.3nm ~ 10µm	0.3nm ~ 10µm		0.3nm ~ 5µm	0.3nm ~ 5µm
Minimum Sample Volume	12µl	12µl		20µl	20µl
Minimum SampleConcentration	0.1mg/mL Lysozyme	0.1mg/mL Lysozyme
Maximum SampleConcentration	40%w/v	40%w/v

** Zeta Potential Measurement

	Nano ZS	Nano S	Nano Z	Nano ZS90	Nano S90
Particle Size Range (Diameter)	3.8nm – 100µm		3.8nm – 100µm	3.8nm – 100µm
Zeta Potential Range	No practical limit		No practical limit	No practical limit
Electrophoretic Range	No practical upper limit		No practical upper limit	No practical upper limit
Conductivity Range	0 to 200mS/cm		0 to 200mS/cm	0 to 200mS/cm
Sample Concentration Range	Up to 40%w/v		Up to 40%w/v	Up to 40%w/v

** Molecular Weight Measurement

Nano ZS

Nano S

Nano Z

Nano ZS90

Nano S90

Absolute Molecular Weight Range

(Debye Plot)

980Da – 2×10⁷Da

9,800Da – 2×10⁷Da

Molecular Weight Range

(Mathematical Diameter)

342Da – 2×10⁷Da

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Zetasizer Nano Series

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