OMNISEC

In size-exclusion chromatography, molecules are separated according to their hydrodynamic radius as they enter and exit the pores of a porous gel packing matrix in the column. Like other HPLC-based techniques, this involves the use of a pump, column and at least one detector to measure the sample as it elutes. An OMNISEC GPC/SEC system includes the following components:

OMNISEC RESOLVE

Pump flow rate:

0.005 - 10 mL/min

Flow rate accuracy:

±1%

Pressure range:

0 - 5000 PSI (34.5 MPa)

Pulsation:

0.15% @ 1 mL/min in water

Dimensions (W, D, H):

420, 640, 890 mm

Weight:

62 kg

Software:

OMNISEC software v10 (or later)

Data acquisition rate:

100 Hz

Patents:

US 14/599,033 "Continuous back seal wash"

AUTOSAMPLER

Capacity:

Up to 192

Sample container types:

HPLC vials or 96-well microtiter plates

Injection volume:

1 - 300 µL

Injection volume accuracy:

>99.5%

Injection volume precision:

<0.3% RSD in full loop mode

<0.5% RSD in partial loop mode

<1% RSD in µL pickup mode

Injection overhead volume:

0 µL in µL pickup mode

Syringe volume:

250 µL standard

Temperature control range:

4 - 60 °C

COLUMN OVEN

Column capacity:

6 x analytical (1 x Tricorn 10/300 GL)

Temperature control range:

20 - 65 °C

OMNISEC REVEAL

Dimensions (W, D, H):

420, 640, 600 mm

Weight:

40 kg

Detector temperature range:

20 - 65 °C

Software:

OMNISEC software v10 (or later)

Data acquisition rate:

100 Hz

Patents:

US20140060162A1 & EP2619543Ba "Modular capillary bridge viscometer"

US20140144214A1 & EP2619544A1 "Automatically balanced capillary bridge viscometer"

Detector 1

Detector:

Light scattering

Measurement principle:

RALS 90° angle, LALS 7° angle

Light source:

50 mW, 640 nm laser

Cell volume:

18 µL

Dynamic range:

2500 mV

Baseline noise:

<0.1 mV

Baseline drift:

<0.2 mV/hr

Detector 2

Detector:

Differential refractive index

Measurement principle:

Deflection

Cell volume:

12 µL

Dynamic range:

±2.5 x 10^-4 RIU

Baseline noise:

<10^-7 RIU

Baseline drift:

<3 x 10^-7 RIU/hr

Detector 3

Detector:

Viscometer

Measurement principle:

4-capillary Wheatstone bridge with self-balancing mechanism and user-exchangeable capillaries

Transducers:

Firmware-based transducer overpressure protection

Detector volume:

17 µL/capillary

Differential pressure baseline noise:

0.3 Pa

Inlet pressure dynamic range:

100 kPa

Inlet pressure baseline noise:

0.01 kPa

Baseline drift:

<0.2 kPa/hr

Detector 4

Detector:

Diode-array-based UV/Vis spectrometer

Wavelength:

190 - 900 nm

Number of wavelengths:

1024

Wavelength accuracy:

<1 nm

Wavelength resolution:

0.6 nm

Cell volume:

7.5 µL

Path length:

10 mm

Baseline noise:

2 x 10^-5 AU

Baseline drift:

5 x 10^-4 AU/hr

Measurement type 1

Measurement type:

Absolute molecular weight

Measurement range:

200 - >10⁷ g/mol

Minimum quantifiable mass:

100 ng of 100kDa molecular weight polystyrene in THF

Measurement principle:

Light scattering (LALS or RALS)

Measurement type 2

Measurement type:

Intrinsic viscosity

Minimum quantifiable mass:

1 µg of 100kDa molecular weight polystyrene in THF

Measurement principle:

4-capillary Wheatstone bridge

Measurement type 3

Measurement type:

Concentration

Minimum quantifiable mass:

100 ng of 100kDa molecular weight polystyrene in THF

Measurement principle:

Differential refractive index detection

Operating environment

Temperature:

15 - 30 °C

Software

Minimum computer specification:

Windows 7 Professional 64 bit, 4th Gen Intel(R) Core I7 Processor (Quad Core HT, 3.4 GHz Turbo, w/ HD Graphics), 8 GB 1600 MHz DDR3 memory, 500 GB 3.5 inch SATA (7200 RPM) HDD, Full-HD monitor

Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.

When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.

Help Desk

• Telephone and email support.
• Operators who take responsibility for your call and ensure your query is answered. 

Training

• User training events

Software downloads

• A simple mechanism for receiving updates and new features

Malvern Panalytical's service options- choose the right plan for you:

	Platinum Plan	Gold Plan	Bronze Visit
Annual PM/PV Test	yes	yes	no
Telephone / Email Support	yes	yes	no
Priority Response	yes	yes	no
Emergency Breakdown visits*	yes	yes	no
Parts Included	yes	no	no
Technical & Software Support	yes	yes	yes
IQ/OQ (Pharma)***	yes	yes	yes

*including labour & travel costs***available at an additional cost