Date recorded: February 18 2013

Duration: 49 minutes 56 seconds

An introduction to Archimedes, the technique of resonant mass measurement, and how this technology is vital in understanding and monitoring early aggregation events in your biopharmaceutical formulation
Table of contents
1. Introduction to ARCHIMEDES “Mass Measurement on a Different Scale”
02:29
2. Agenda
00:49
3. 700 Malvern employees worldwide
01:01
4. The Biopharmaceutical Shift
01:09
5. Malvern’s Commitment to Biopharma
01:49
6. ARCHIMEDES Preview
01:08
7. How ARCHIMEDES Works
00:07
8. Technology: Resonant Mass Measurement
00:23
9. Measuring Particle Mass in Fluid
00:42
10. Measuring Particle Mass in Fluid
00:25
11. Sensors Fabricated via MEMS
01:58
12. ARCHIMEDES’ Instrumentation
01:23
13. ARCHIMEDES in Action
00:28
14. 2 Micron Particles
00:28
15. Particle Properties and Statistics
00:37
16. Superior Particle Metrology
00:45
17. ARCHIMEDES: a Complete System
00:41
18. ARCHIMEDES for Analysis of Protein Formulations
00:07
19. ARCHIMEDES Addresses a Key Size Range
01:07
20. ARCHIMEDES’ Analysis of Human IgG
01:09
21. Silicone Oil in Protein Formulations
01:01
22. ARCHIMEDES distinguishes silicone oil from protein by buoyancy
00:56
23. ProteinOilTurboTrace
00:24
24. Comparison of IFN-Beta Products for Multiple Sclerosis with Jim Barnard and John Carpenter, U. Colorado
01:52
25. ARCHIMEDES’ Analysis of Aggregates vs. Oil in IFN-Beta Products
01:09
26. Method Comparison
01:03
27. Development of Aggregates in Stressed Protein Formulations
01:47
28. Determining Particle Density
01:38
29. ARCHIMEDES’ Advantages for Protein Characterization
01:26
30. Further Applications of ARCHIMEDES
00:10
31. Nanoparticles: 57 nm + 100 nm Au
00:37
32. Bacteria and Cell Growth
02:25
33. References
00:19
34. For Further Information
12:06
35. Closing Slide
04:18