Volume, density, and porosity are interrelated parameters widely recognized as important for the control of drug product manufacture. Tableted medicines need to be a consistent size and shape for efficient packaging and patient acceptability.
Envelope density can be a useful check of tablet consistency, since it may be influenced by the extent of compaction, while the skeletal density of a granulated tableting blend may be controlled to achieve acceptable flowability or compressibility in the press.
Volume, density, and porosity are interrelated parameters widely recognized as important for the control of drug product manufacture. Tableted medicines need to be a consistent size and shape for efficient packaging and patient acceptability.
Envelope density can be a useful check of tablet consistency, since it may be influenced by the extent of compaction, while the skeletal density of a granulated tableting blend may be controlled to achieve acceptable flowability or compressibility in the press.
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