Login Register
Edit profile

Zetasizer Range

Particle and molecular size/charge analyzers

From versatile cuvette-based particle characterization to high-throughput biotherapeutic stability screening: choose the platform built for your workflow.

Download brochure View Models
Zetasizer Range

Which Zetasizer platform fits your lab?

Choose the Zetasizer Advance range if you need:

  • Zeta potential and particle mobility: Electrophoretic mobility and zeta potential measurements via patented M3-PALS technology.
  • Low volume & high resolution: Versatile, high quality particle sizing from 0.3nm o 15um, higher resolution DLS by use of multiangle dynamic light scattering (MADLS) and single sample volumes as low as 1uL.
  • Versatile sample types: Broad sample compatibility ranging from proteins, nanoparticles, quantum dots, and polymers to emulsions and ceramics across custom cell types.
  • Flexible automation: Modular, on-site upgradeability and optional automated sample handling with the Zetasizer Sample Assistant.

Choose the Zetasizer Core if you need:

  • High-throughput screening: Automated, unattended 96-, 384-, and 1536- microwell plate reading for rapid candidate screening and formulation libraries.
  • Combined thermal & colloidal stability: Simultaneous assessment of conformational stability (melting temperature Tm via DSF) and colloidal stability (kD and B22 via DLS/SLS).
  • Early biotherapeutic candidate selection: Rapidly identify lead antibodies, viral vectors, or recombinant proteins with optimal thermal and aggregation resistance.
  • Integrated multi-technique analytics: High-volume data acquisition from a single plate setup without switching instruments between sizing and fluorescence assays.

Contact us for help choosing the right option

Need guidance on selecting between cuvette characterization and high-throughput plate screening?

Our application specialists can help evaluate your sample throughput, assay types, and analytical goals to match you with the right platform.

Contact us

How our products compare

  • Zetasizer Advance Range

    Light Scattering for every application

    Zetasizer Advance Range

    Platform category

    • Cuvette & cell-based characterization

    Core strengths

    • Comprehensive particle sizing, Zeta potential and particle mobility, concentration, and sub-nanometer resolution.

    Key technologies

    • Dynamic light scattering (DLS), NIBS technology, Multi-angle DLS (MADLS), Static light scattering (SLS), Electrophoretic light scattering (ELS) with M3-PALS

    Primary output metrics

    • Hydrodynamic diameter (dH), zeta potential/charge, particle concentration, colloidal stability (B₂₂, kᴅ), molecular weight (kDa)

    Format & throughput

    • Individual cuvettes, capillary cells, dip cells, or automated sample loader (Sample Assistant)

    Target workflows

    • Versatile R&D, advanced formulation, nanomedicines, polymers, colloids, and compliance QA/QC

    Included models

    • Zetasizer Ultra | Pro | Lab
    More details Request a quote

  • Zetasizer Core

    Next generation biophysical screening at scale

    Zetasizer Core

    Platform category

    • High-throughput microplate screening

    Core strengths

    • Multi-parameter stability, thermal unfolding, sizing, and colloidal stability profiling in microplates.

    Key technologies

    • Dynamic light scattering (DLS), Linear static light scattering (SLS), Intrinsic differential scanning fluorimetry (DSF)

    Primary output metrics

    • Thermal stability (Tₘ), aggregation onset (Tₒₙₛₑₜ), colloidal stability (B₂₂, kᴅ), hydrodynamic diameter (dH), molecular weight (kDa)

    Format & throughput

    • Standard 96-, 384- and 1536- well microplate screening for automated, high-throughput workflows

    Target workflows

    • Biotherapeutic discovery, early candidate selection, protein formulation development, and high-throughput stability screening

    Included models

    • Zetasizer Core-DSF | Zetasizer Core
    More details Request a quote

Trust Every Result with the Zetasizer family.

Accelerate decisions with confidence using the Zetasizer Advance, combining industry leading particle characterisation, intelligent automation and compliant data integrity in one powerful platform.

  • Higher-resolution particle sizing with MADLS
  • Precise Zeta Potential for stability prediction
  • Automated workflows with the Sample Assistant
  • Regulatory-ready compliance with OmniTrust
  • Faster, smarter results with Adaptive Correlation

Trusted data. Faster workflows. Lower risk. Better outcomes.

Request a quote