Date recorded: May 05 2011

Duration: 01 hours 05 minutes 16 seconds

Here we describe the use of the Spraytec in optimizing the performance of pharmaceutical inhaler and nebuliser systems.
Table of contents
1. Inhaler and nebulizer characterization
01:17
2. Inhaler and nebuliser characterisation
00:30
3. Inhaled drug deposition: important parameters
01:50
4. Spray characterisation: cascade impaction
01:42
5. Cascade impaction: advantages and disadvantages
02:06
6. Spray characterisation: why use laser diffraction?
02:25
7. How do laser diffraction systems measure particle size distributions?
01:16
8. How do laser diffraction systems measure particle size distributions?
01:13
9. Spraytec light scattering data
01:16
10. Comparing laser diffraction within cascade impaction
03:34
11. Laser diffraction: accessories for pharmaceutical spray measurements
01:20
12. What information does laser diffraction provide?
01:56
13. Dry Powder Inhalers: overview
00:51
14. A common view of dry powder dispersion…
00:50
15. The device and formulation must be considered together…
01:10
16. Hypothesis for dry powder delivery
00:41
17. Laser Diffraction study: experimental detail
01:14
18. Particle size flow rate dependence for the unprocessed lactose powder
00:53
19. Particle size flow rate dependence for the blended lactose / MgSt sample
00:39
20. Particle size flow rate dependence for the mechanofused lactose / MgSt sample
00:42
21. Concentration as a function of time for the blended lactose / MgSt sample
00:53
22. Concentration as a function of time for the mechanofused lactose / MgSt sample
00:59
23. Co-processing fine powders leads to changes in aerosolisation behaviour…
01:07
24. Co-processing fine powders leads to changes in aerosolisation behaviour…
00:22
25. Malvern Image Analysis Instrumentation
01:23
26. How does image analysis work?
01:16
27. Using shape to quantify agglomerates
02:09
28. Scattergram - Agglomerates
01:39
29. Scattergram – Primary Particles
00:45
30. Scattergram - Excipient Particles
00:58
31. Carrier free formulations
01:23
32. Effect of coating on circularity
01:42
33. Effect of coating on dispersion
01:29
34. Effect of coating on emitted dose
02:03
35. Nebulisers: overview
01:38
36. Gas-driven jet nebuliser performance
01:11
37. Breath-assisted nebuliser operation
01:42
38. Breath-assisted nebuliser operation: size histories for different breathing rates
00:41
39. Breath-assisted nebuliser operation: profiles for different formulation viscosities
01:01
40. Acknowledgements
00:18
41. Conclusions
01:02
42. Comparing laser diffraction within cascade impaction
03:27
43. Contact Information
08:43