Date recorded: March 18 2015

Duration: 51 minutes 24 seconds

The use of nanoparticles as drug delivery vehicles has seen a large amount of research and investment over the last decade as they have the potential for great benefits in the targeting and efficacy of drug treatments. The interest in them is largely to do with the ability to use them as drug carriers and/or complete surface modifications which can assist in targeting within the body.

Despite the substantial research and interest in the arena, there is still great difficulty in understanding the amount of loading within or on the surface of these drug delivery vehicles. This webinar provides an overview of some of the research within the arena and in particular around nanoparticle surface modifications, along with providing some research data on how recent developments in resonant mass measurement characterization tools can greatly assist in understanding the amount of material within or on the (nanoparticle) carrier.

Table of contents
1. A fantastic voyage through the arena of nanoparticle drug delivery
00:50
2. A fantastic voyage through the arena of nanoparticle drug delivery
00:34
3. Our laboratory
01:29
4. Adsorption and protein pharmaceuticals
02:32
5. Dynamic Light Scattering (DLS)
02:01
6. Nanoparticle Tracking Analysis (NTA)
00:52
7. Archimedes system
00:19
8. Archimedes system - principle
01:46
9. Archimedes system - principle
00:56
10. Archimedes system - principle
01:08
11. Summary of techniques
00:56
12. Data analysis
01:50
13. Data analysis
01:21
14. 600 nm particles, 0.05 mg/ml BSA
02:44
15. Mass and surface coverage for 600 nm and 1 µm particles
03:08
16. Mass and surface coverage for 600 nm and 1 µm particles
02:42
17. Adsorption from BSA solutions of 0.5, 0.05 and 0.005 mg/mL
01:43
18. Adsorption from IgG solutions of 0.05 mg/mL
01:35
19. Conclusions
00:44
20. Mass and surface coverage for 600 nm and 1 µm particles
00:39
21. Thank you for your attentionAny questions?
20:18
22. Contact Information
01:17
23. Thank you for watching
00:00