Date recorded: July 08 2015
Duration: 55 minutes 32 seconds
From simple food additives to complex material used in high-tech eye surgery and targeted drug delivery systems, polysaccharides have earned unparalleled attention when it comes to macromolecular characterization. With more emphasis on product performance, versatility and stability; detailed characterization is the key to understanding important parameters that affect the quality of these products. Simple techniques stand unable to provide the answers needed.
Gel Permeation Chromatography (GPC), or Size Exclusion Chromatography (SEC), is the technique of choice for rapid and reliable determination of molecular weight and molecular structure for all types of macromolecules. Furthermore, in the last 20 years there has been a significant change to the way GPC/SEC has been used in polymer and biologics analysis.
Measurement of polysaccharide molecular weight, size, branching and intrinsic viscosity can highlight the differences in product performance due to a change in polymer structure and those differences that are caused by a change in molecular weight.
This webinar will focus on the advancements in light scattering and on-line viscometry techniques and the benefits they provide to the technique of polysaccharide characterization by GPC/SEC. The fundamentals of these measurements will also be discussed and illustrated with application examples.