Accelerating the deformulation workflow for oral solid dosage forms
by Dr Deborah Huck-Jones, Product Manager, Analytical Imaging and Dr Paul Kippax, Product Group Manager, Malvern Instruments Ltd. | 09 December 2014
Oral Solid Dosage (OSD) forms still represent a significant share of the pharmaceutical market. As a result, they remain an important target for generic product developers. In this white paper we introduce a workflow for OSD product deformulation and demonstrate how component specific particle size and shape data, obtained using Morphologically Directed Raman Spectroscopy (MDRS), can aid the preparation of a successful ANDA submission.
