Automated particle size measurement for the Zetasizer Nano

The Zetasizer NanoSampler is a sample delivery system that ensures highly precise and reproducible automated loading of samples into your Zetasizer Nano. The NanoSampler adds automation and unattended operation in a versatile, compact package, maximising the productivity of your Zetasizer Nano. While the benefits of automated operation are useful for all users, the NanoSampler is ideally suited for laboratories where a large number of measurements are required and reproducibility or multi-variate studies are important.

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The Zetasizer NanoSampler can accommodate up to 96 sample vials, accurately delivering up to 3 sequential aliquots of each sample into the Zetasizer Nano for automated particle size or molecular size measurements. All operation remains within the easy-to-use Zetasizer software using the simple Standard Operating Procedure (SOP) interface. The NanoSampler is delivered complete with the software, analysis cell and fittings to attach to the Zetasizer Nano instrument.

  • Automated measurements reduces operator bias and improves laboratory efficiency
  • Unattended multi-variate analysis simplifies exploration of the effect of key formulation parameters
  • Compatible with any Zetasizer Nano for measurement of size
  • Automates reproducibility studies
  • Improved sample throughput
  • Reduced operator time
  • Maximizes the return on your Zetasizer investment
  • Simple change over from automated to manual measurements

How it works

The NanoSampler is delivered complete with the software, analysis cell and fittings to attach to the Zetasizer Nano instrument.

A license key, supplied with the NanoSampler, enables control of the autosampler from the Zetasizer software. A Standard Operating Procedure allows the user to select which vials to analyze.

You need at least 750µL for one loading, which is pumped through the tubing and into the quartz flow cell fitted inside the Zetasizer Nano instrument. Size measurements are then made before the next sample is analyzed automatically. Up to three repeat measurements can be made from a full 1.5mL vial if required.



Sample capacity 96 x 1.5 mL vials in 2 plates
Minimum sample volume for single loading 750 µL
Injections per vial 1-3 programmable
Maximum sample viscosity 6.44 cP
Carryover <0.05%*
Communication port USB 2.0
Power 95 – 240 Vac +/- 10%, 50-60 Hz

Weight and dimensions

Dimensions (W, D, H) 300mm x 510mm x 360mm
Weight 19 kg

Operating environment

Temperature 10°C – 40°C
Humidity 20% - 80% non-condensing
Note *sample dependent