Part two: Formulation and Process Development

The second webinar in our three-part series explores formulation and process development.

In this session we will explore stability assessment, demonstrating how thermal and structural solid form analysis methods can be used in a complimentary way. Thermal analysis (Differential Scanning Calorimetry, DSC and Thermogravimetric Analysis, TGA) can be used to assess transition temperatures (and respective energies) of drug substances. Structural analysis structural (X-Ray Powder Diffraction, XRPD) will provide details on respective phases and solid forms that appear in response to temperature changes. A similar approach is applied to experiments involving changes in relative humidity values. Even complex behavior, with the formation of different (mono-, di-, tetra-, etc.) hydrates can be easily understood through building phase diagrams based on such experiments. 

We will also explain why particle size and shape characterization is critical to ensuring robust formulation (with appropriate process parameters) and how this can be achieved. 

You will also have the option to ask questions to our experts, Dr Gabriele Kaiser, Dr David Fengas and Dr Natalia Dadivanyan. If this time doesn’t suit you, register for the later session here

Join our upcoming series of "Everything pharmaceutical scientists need to know about solid form characterization"

  • Webinar 1: API selection. Register here
  • Webinar 2: Formulation and Process Development
  • Webinar 3: Characterizing amorphous materials. Register here

Summary

Measurement type:
Crystal structure determination
Phase identification
Date:
October 28 2021 - October 28 2021
Time:
10:30 - 11:30
Eastern Time [US & Canada]
Event type:
Webinar - Live
Language:
English
Products:
Aeris range
Empyrean range
Mastersizer 3000
Morphologi 4
Technology:
X-ray Scattering
X-ray Diffraction (XRD)
Laser Diffraction
Morphologically Directed Raman Spectroscopy (MDRS)
Differential Scanning Calorimetry (DSC)
Industry:
Pharmaceutical formulation development
Pharmaceutical

Agenda

What will you learn?

  • Expand your knowledge of API characterization
  • Learn about stability assessment and get insight on shelf life behavior
  • Learn about the influence of particle size and form on formulation properties
  • Refresh your knowledge of X-ray diffraction, thermal analysis and particle size and shape characterization methods

Speakers

  • Dr Gabriele Kaiser - Business Field Manager Pharmacy, Cosmetics and Food, Netzsch
  • Dr Robert Taylor - Product Technical Specialist, Malvern Panalytical
  • Dr Gwilherm Nenert - Application Specialist XRD, Malvern Panalytical

More information

Who should attend?

  • Anyone involved in formulation and process optimization
  • Anyone engaged in stability studies
  • Anyone developing pharmaceutical formulations