Join us and our guest speaker, Mariana Hugo Silva, who will present a real-world case study on characterizing lipid nanoparticles using dynamic light scattering (DLS), differential scanning calorimetry (DSC), asymmetric flow field flow fractionation (AF4-MALS-RI-DLS) and cryogenic transmission electron microscopy (Cryo-TEM).
Discover how the integration of DSC as part of a comprehensive analytical toolbox helps to better understand the structural changes occurring in mRNA-LNPs when subjected to different stress factors.
Speakers
- Mariana Hugo Silva - Ghent Research Group on Nanomedicines, Ghent University
- Natalia Markova - Head of Science - Pharmaceutical & Food, Malvern Panalytical
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Who should attend?
- If you're working at the cutting edge of mRNA therapeutics, lipid nanoparticles, or advanced drug delivery systems, this webinar is for you.
- Whether you're a scientist, researcher, or industry professional in formulation, analytics, stability testing, or quality control you'll gain valuable insights to enhance your approach to LNP characterization.
What will you learn?
- The value of integrating DSC into a broader analytical toolbox to gain deeper insights into nanoparticle behaviour alongside other techniques
- How DSC and complementary methods work together to reveal structural changes in mRNA-LNPs under different stress conditions
- Practical insights and lessons from a real-world case study, including challenges in LNP characterization and what these changes mean for formulation and process development
- Important considerations for data interpretation and troubleshooting during LNP analysis