OMNISEC

Malvern Panalytical's OMNISEC is a Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) system for the measurement of absolute molecular weight, molecular size, intrinsic viscosity, branching and other parameters. It includes OMNISEC RESOLVE, the integrated GPC/SEC module, OMNISEC REVEAL, the integrated multi-detector module and OMNISEC software for the characterization of synthetic and natural polymers, and proteins. The SEC-MALS detector complements RALS/LALS or can be used as the sole light scattering detector.

The OMNISEC system reached end of manufacture in May 2025. 

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User manuals

Software downloads

25 October 2021

2.21

Malvern Access Configurator (MAC) software
  • Security and maintenance release. See SUN for details.
2.21

26 June 2018

2.20

Malvern Access Configurator (MAC) software
  • Searching and exporting the audit history
2.20

05 September 2017

2.10

Malvern Access Configurator (MAC) software
  • Initial release
2.10

11 December 2024

11.42

11.42 - Bug fixes surrounding rendering failure, refer to the Software Update Notification (SUN) document for more details.

11.42

02 October 2023

11.41

11.41 - Maintenance and bug fixes, refer to the Software Update Notification (SUN) document for more details.

11.41

21 December 2022

11.40

Automated Analysis

Numerous bug fixes, refer to the Software Update Notification (SUN) document for more details.

11.40

06 October 2022

11.37

Flow Rate Markers and Mass Markers.

Calculation options to enable transfer of TDA methods.

Numerous bug fixes, refer to the Software Update Notification (SUN) document for more details.

11.37

11 July 2022

11.36

This is a maintenance release and addresses many known issues. There are no features changes in this release. 

11.36

14 March 2022

11.35

This software release supports  a new firmware version 1.7002 added to the install of OMNISEC.

The installation of this firmware version will allow the installation engineer to set the DP transducer as either a 5kPA or 100kPa transducer.

11.35

24 January 2022

11.33

Bug fix release, refer to the Software Update Notification (SUN) document for more details.

11.33

08 July 2021

11.32

Bug fix release, refer to the Software Update Notification (SUN) document for more details.

11.32

14 June 2021

11.31

- MALS Model/Fit View fit order and include/exclude points [Requires 21 CFR feature key]

- Update plot colours in analysis view and report widgets

- Report Concentration A/Concentration B [Requires compositional analysis feature key]

Refer to the Software Update Notification (SUN) document for more details.

11.31

29 March 2021

11.30

Compositional Analysis

Refer to the Software Update Notification (SUN) document for more details.

11.30

02 December 2020

11.22

- Maintenance Release

Refer to the Software Update Notification (SUN) document for more details.

11.22

02 October 2020

11.21

- Maintenance Release

Refer to the Software Update Notification (SUN) document for more details.

11.21

11 June 2020

11.20

- Column calibration methods.

- Improvements to the calculation method editor.

Refer to the Software Update Notification (SUN) document for more details.

11.20

11 December 2019

11.10

Refer to the Software Update Notification (SUN) document for new features.

11.10

06 August 2019

11.01

Refer to the Software Update Notification (SUN) document for new features.

11.01

03 July 2019

11.00

Refer to the Software Update Notification (SUN) document for new features.

11.00

05 October 2018

10.41

  • Transducer overpressure protection improvements
  • Automated pump back seal washing system
10.41

19 June 2018

10.40

  • Windows 10 Support
  • Data deletion capability
10.40

01 February 2018

10.31

  • Maintenance release
10.31

21 August 2017

10.30

  • New features release
  • Protein Method
  • 21 CFR features
  • Additional Record parameters
10.30

27 September 2016

10.20

  • New features release
  • Intrinsic viscosity distribution
  • Advanced data selector view
  • Additional Record parameters
10.20

01 June 2016

10.10

  • New features release
  • Only compatible with English operating systems (US/UK)
10.10

13 January 2016

10.02

  • Maintenance release
10.02

01 September 2015

10.0

  • First release.
10.0

Events and training

All events
Webinar - Recorded
Complementary techniques for biophysical characterization of peptides and protein-based drug products

November 2024 | English

Complementary techniques for biophysical characterization of peptides and protein-based drug products

Products:
MicroCal range, Zetasizer Advance Range, OMNISEC system, Zetasizer range, MicroCal DSC range
Technology:
Differential Scanning Calorimetry (DSC), Multi angle light scattering, Size Exclusion Chromatography (SEC), Dynamic Light Scattering, Small Angle X-ray Scattering (SAXS), Microcalorimetry
Industry:
Biologics, Pharmaceutical
Complementary techniques for biophysical characterization of peptides and protein-based drug products
Webinar - Recorded
Webinar Desvendando a cadeia analítica das tintas e revestimentos: da matéria-prima à aplicação final

September 2024 | Portuguese

Webinar Desvendando a cadeia analítica das tintas e revestimentos: da matéria-prima à aplicação final

Products:
Epsilon range, Mastersizer range, OMNISEC system, Zetasizer range, Zetium
Technology:
Gel Permeation Chromatography, Laser Diffraction, X-ray Fluorescence (XRF), Light Scattering, Multi-Angle Dynamic Light Scattering (MADLS)
Industry:
Chemicals/Coatings
Webinar Desvendando a cadeia analítica das tintas e revestimentos: da matéria-prima à aplicação final
Webinar - Recorded
Advanced Dairy Analysis: Leveraging Cutting-Edge Techniques for Quality, Safety, and Innovation

September 2024 | English

Advanced Dairy Analysis: Leveraging Cutting-Edge Techniques for Quality, Safety, and Innovation

Products:
Revontium, Zetasizer Advance Range, Zetasizer range, ASD range, Mastersizer range, OMNISEC system, Empyrean range, Epsilon range
Technology:
X-ray Fluorescence (XRF), Dynamic Light Scattering, Laser Diffraction, Size Exclusion Chromatography (SEC), Light Scattering, Near-infrared Spectroscopy (NIR)
Industry:
Food and Beverages
Advanced Dairy Analysis: Leveraging Cutting-Edge Techniques for Quality, Safety, and Innovation
Webinar - Recorded
Lipid nanoparticles for drug delivery

September 2022 | English

Lipid nanoparticles for drug delivery

Products:
Zetasizer range, OMNISEC system, MicroCal PEAQ-DSC, NanoSight range
Technology:
Size Exclusion Chromatography (SEC), Differential Scanning Calorimetry (DSC), Multi-Angle Dynamic Light Scattering (MADLS), Dynamic Light Scattering
Industry:
Biologics, Pharmaceutical
Lipid nanoparticles for drug delivery