Zetasizer Advance Series User Guide (English)
Version number: MAN0592-15-EN
Zetasizer Pro
The new Zetasizer Pro is your go-to instrument to measure a wide range of sample types and concentrations. It offers wide dynamic concentration capability and high sensitivity due to the Non-Invasive Back Scatter (NIBS) optical design. Measurement of particle size, molecular size, electrophoretic mobility, zeta potential and molecular weight can all be performed with ease.
The Adaptive Correlation feature enhances sample throughput by reducing measurement duration and providing greater sample knowledge. The deep learning-based data quality system gives you the confidence to know your data is the best it can be.
The optical filter wheel allows measurement of fluorescent samples without impacting overall instrument sensitivity.
Works with OmniTrust: Malvern Panalytical's compliance solution for the regulated environment
User manuals
Zetasizer Advance Series Basic Guide (English)
Version number: MAN0593-10-EN
Zetasizer Advance Series Accessories Guide (English)
Version number: MAN0604-05-EN
Zetasizer Advance Series Basic Guide (German)
Version number: MAN0593-05-EN
Software downloads
3.31
Maintenance release, updates to key services and addition of Titration summary data logs.
See SUN for full details.
3.30
ZS Xplorer version 3.3 extends OmniTrust support to the Studies features of the main application. Previously OmniTrust users were prevented from accessing Studies to prevent un-audited events. From 3.3 OmniTrust users can now access Studies for Molecular Weight and associated parameters with permissions and auditing of events within the Studies features.
Note that Studies by their nature are intended for advanced users and to be flexible in their analysis. Users not requiring Studies features can still prevent access to these features using permissions in OmniAccess.
Version 3.3 also addresses a few minor bug fixes.
See SUN for full details.
3.22
ZS Xplorer 3.2.2 has the following updates:
Software re-branded to Malvern Panalytical brand
Minor bug fixes - one of which may have prevented instrument connection
Bug fix for OmniTrust users that meant editing of records was possible, even when user permission for this action was disabled (recommended update for OmniTrust users currently on ZS Xplorer 3.2.1.)
Updated Toluene calibration routine to prevent incorrect reporting of issues with calibration.
See SUN for full details.
3.21
ZS Xplorer 3.2.1 adds Smart Instrument enrollment - the first step in bringing Zetasizer into Malvern Panalytical's Smart Manager services.
Several installer improvements have been made to reduce ZS Xplorer requirements around .NET and WebView2 components.
We have also added ability to edit peak thresholds for size measurements and refinements on CSV exporting from parameter tables.
See SUN for full details.
3.20
ZS Xplorer version 3.2.0 adds upper and lower display range configuration for Size/MADLS & Particle Concentration measurements.
Introduces Data Quality Advice for MADLS & Particle Concentration measurements.
Adds further Trend analysis improvements and bug fixes.
Extends Japanese and Chinese localization to Studies and Data Quality Advice.
Adds speed and robustness improvements to Scattering standard measurements.
Other improvements and bug fixes.
See SUN for full details.
3.10
ZS Xplorer version 3.1.0 extends studies and concentration trend measurements to support the Zetasizer Advance Lab models and also adds the capability to perform concentration trends in either back or side scatter on Zetasizer Advance Ultra models. Concentration trends also now supports setting of measurement temperature and adds display of R2 value to tables and graphs.
Exporting of data to CSV file from graphs and tables in Concentration trends and from Parameter and Statistic tables in Analyze views has been introduced.
Data quality advice for Zeta potential measurements has been further refined to provide users with better diagnosis of sample/measurement issues.
Exporting a study now provides an option to include the results data for transfer of the complete study between data repositories.
Various bug fixes, see software update notification for details.
3.00
ZS Xplorer version 3.0.0 introduces studies and concentration trend measurements for the determination of molecular weight by static light scattering and kD by dynamic light scattering. Note: This first release does not support Zetasizer Lab or OmniTrust users. Auto averaging for Zeta, MADLS and Particle concentration has also been added along with other quality of life features and bug fixes. See SUN for details.
2.31
ZS Xplorer version 2.3.1 introduces post-analysis averaging for Zeta, Particle Concentration and MADLS size measurements. Zeta mobility parameters and graphs have
been added, as well as a count rate meter and
localization for Chinese (Simplified) and Japanese language support.
Important: This version supports OmniTrust 1.4.0; OmniTrust users should upgrade their installation to 1.4 if upgrading to ZS Xplorer 2.3.1.
2.30
ZS Xplorer version 2.3.0 introduces post analysis averaging for Zeta, Particle Concentration and MADLS size measurements. Zeta mobility parameters and graphs have also been added, as well as a count rate meter.
Important: This version supports OmniTrust 1.4.0; OmniTrust users should upgrade their installation to 1.4 if upgrading to ZS Xplorer 2.3.0.
details.
2.20
- Maintenance release see Software Update Notification for details.
2.10
- ZS Xplorer 2.1 offers improvements to OmniTrust regulated environment users by providing improved control of methods and provision of a method audit trail. This version also provides improvements by provision of major size distribution percentiles and automatic size averaging function. A critical bug that could affect zeta potential data for very low scattering samples has also been fixed. See the Software Update Notification for more details.
2.01
- Bug fix: Changing sample details on locked methods
- Fixed a bug around method permissions for OmniTrust regulated environment users that prevented editing of method sample details.
1.60
OmniAccess
- Flexible/configurable roles in Empyrean and Aeris (now aligns with Zetasizer)
- Summary of roles/permissions
- Default roles for instrument applications
- Support for complex domains
- Wizard for initial set up and massively improved UI to improve configuration/set up
OmniTrail
- Record Audit trail events viewable in OmniTrail.
- Show/compare authorization files
More information can be found in the Release and Installation Notes.
1.40
OmniAccess
- Flexible/configurable roles in Empyrean and Aeris (now aligns with Zetasizer)
- Summary of roles/permissions
- Default roles for instrument applications
- Support for complex domains
- Wizard for initial set up and massively improved UI to improve configuration/set up
OmniTrail
- Record Audit trail events viewable in OmniTrail.
- Show/compare authorization files
More information can be found in the Release and Installation Notes.
Accessories
Configure the Zetasizer Pro for your applications and requirements with our range of configuration options:
Accessories
SV-10 viscometer
Viscosity measurement with speed, simplicity and accuracy.
The SV-10 measures viscosity with the accuracy required for dynamic light scattering, for the conversion of diffusion speed to size, and electrophoretic mobility to zeta potential, in an extremely simple and rapid system.
MPT-3 Autotitrator
Automate your pH titrations
The MPT-3 is a cost-effective accessory for the Zetasizer Advance range, designed to automate your Zeta and/or Size vs. pH titrations, helping you understand how your materials behave as a function of pH.
The zeta potential and/or size of your materials with pH changes can be critical in understanding:
- Material stability
- Agglomeration
- Flocculation
- Point of net-zero charge (isoelectric point)
- Storage conditions
Cell & cuvette options
Disposable folded capillary cell (DTS1070)
Eliminate sample cross contamination between zeta potential measurements using a completely disposable cell.
The zeta potential of colloids and molecules is extremely sensitive to contamination from components of a previous sample used in a measurement cell. The use of a disposable cell completely eliminates this potential contamination issue.
The folded capillary cell provides the benefits of the accuracy of measurement of a capillary cell with the ease of use of a disposable cell.
Although, disposable, including the electrodes, for low conductivity samples each cell can be used for hundreds of measurements if required.
The cell can be used with the autotitrator, where multiple measurements are routinely done over a wide pH range.
Universal 'dip' cell kit
Reusable solvent resistant cell.
The dip cell is used for the measurement of zeta potential of samples in aqueous and non-aqueous dispersants, and is designed to be cleaned and reused. It is for batch measurements using standard polystyrene or glass cuvettes.
High concentration zeta potential cell kit
Save time and effort by measuring zeta potential with little or no dilution.
The high concentration cell enables the measurement of the zeta potential of samples with little or no dilution in any Zetasizer Advance system that measures zeta potential.
The cell has a flow configuration so can be used for stop-flow size and zeta potential measurements using an MPT-3 autotitrator as well as batch measurements.
12mm square glass cell (PCS8501)
Glass cuvette for batch measurements.
- For size and molecular weight measurements
- Compatible with aqueous and non-aqueous solvents and dispersants
12mm Glass cell (PCS1115)
Glass cuvette for use with the dip cell.
- For size and zeta potential measurements using the ‘dip’ cell
- Compatible with aqueous and non-aqueous solvents and dispersants
Low-volume quartz batch cuvette (ZEN2112)
Low-volume quartz batch cuvette for size and molecular weight measurements.
- Compatible with size and molecular weight measurements with aqueous and non-aqueous solvents and dispersants
- Minimum sample volume 12 microliters
- Maximum volume 45 microliters
12mm Square Polystyrene Cuvettes (DTS0012)
Disposable polystyrene cuvettes.
- 100 disposable cells complete with 100 stoppers to avoid cross-contamination
- For size measurements using aqueous dispersants
- Compatible with zeta potential measurements using the dip cell
Disposable Solvent Resistant Micro Cuvette (ZEN0040)
Disposable plastic micro cuvette, for size measurement at 173° (NIBS) optics only.
- 100 x 40µL cuvettes with 100 caps to avoid cross-contamination
- Compatible with aqueous samples and a range of other solvents: Acetone, Benzaldehyde, Butanone, Dioxane, DMF, Ethyl acetate, Isopropanol, plus various acids and bases
Events and training
All events
Optimizing microfluidics: Liposome & LNP production
- Products:
- Zetasizer Advance Range, Zetasizer Lab, Zetasizer Pro, Zetasizer Ultra
- Technology:
- Dynamic Light Scattering, Multi-Angle Dynamic Light Scattering (MADLS)
Discover Zetasizer Advance - Meet the New Line-up of Dynamic Light Scattering Instruments from the Pioneers of DLS Technology
- Products:
- Zetasizer Pro, Zetasizer Ultra
- Technology:
- Multi-Angle Dynamic Light Scattering (MADLS), Dynamic Light Scattering
- Industry:
- Pharmaceutical
Particle Sizing Masterclass: When to Use Laser Diffraction and When to Use Dynamic Light Scattering - A Practical Guide
- Products:
- Zetasizer Nano range, Mastersizer range, Spraytec, Insitec range, Zetasizer Pro, Zetasizer Ultra
- Technology:
- Dynamic Light Scattering, Laser Diffraction
- Industry:
- Nanomaterials
DLS, PCS, QELS, NIBS, MADLS, ELS - Oh my!
- Products:
- Zetasizer range, Zetasizer Nano range, Zetasizer Pro, Zetasizer Ultra
- Technology:
- Light Scattering, Dynamic Light Scattering
Support contract options
Protect your investment and ensure optimized performance at all times with Malvern Panalytical's service plans.
When you purchase a Malvern Panalytical product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern Panalytical will provide the support for your business.
Help Desk
- Telephone and email support.
- Operators who take responsibility for your call and ensure your query is answered.
Training
- User training events
Software downloads
Malvern Panalytical's service options- choose the right plan for you:
Malvern Panalytical Platinum Plan
For laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.
Malvern Panalytical Gold Plan
Enhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.
Malvern Panalytical Bronze Visit
For laboratories looking to optimize instrument performance, regular preventative maintenance is essential.
| Platinum Plan | Gold Plan | Bronze Visit | |
|---|---|---|---|
| Annual PM/PV Test | yes | yes | no |
| Telephone / Email Support | yes | yes | no |
| Priority Response | yes | yes | no |
| Emergency Breakdown visits* | yes | yes | no |
| Parts Included | yes | no | no |
| Technical & Software Support | yes | yes | yes |
| IQ/OQ (Pharma)*** | yes | yes | yes |
*including labour & travel costs ***available at an additional cost